Laserfiche WebLink
it* V <br />r: <br />r <br />' j <br />^ • I <br />■1. <br />- • s' <br />■'M. <br />&• ^ ^-: <br />Ut <br />3Hy <br />■:i.i <br />r\“ <br />/•: <br />I- <br />F <br /><-■•-•. <br />■W^‘. <br />F -c'V <br />r‘--^r-Iji <br />">• <br />V- <br />■ <br />''ffk <br />U-i <br />w-r <br />|:r <br />92-47.08 <br />In Sluuuiry, the two main conclusions of this study are: <br />This study predicts no adverse health effects resulting from <br />the use of TAP in this demonstration project, because the <br />noncarcinogenic health effects are calculated to be below <br />the U.S. EPA goal, and the potential carcinogenic risks are <br />estimated to be well within or below the U.S. EPA acceptable <br />of 10'‘ to lO’ excess cancer risks.range <br />All three alternatives considered in this study are safe, <br />based on the results of this study. <br />UNCERTAINTY ANALYSIS <br />A semi-quantitative uncertainty analysis was performed on <br />the various factors contributing to the risks developed in this <br />risk assessment. Such factors include uncertainties arising from <br />sampling procedures, chemical analysis, toxicological parameters <br />(i.e., carcinogenic slope factors and non-carcinogenic reference <br />doses), and uncertainties in the variables used to estimate <br />chemical intakes. These intake variables include such factors as <br />chemical intake, chemical concentration, contact rate, exposure <br />frequency, and duration and body weight. <br />The uncertainty analysis conducted for this project revealed <br />that a wide range of uncertainty (several orders of magnitude or <br />greater) exist, with most of the uncertainty being in the <br />conservative direction because of the conservative assumptions <br />used in this assessment. This means that there is a substantial <br />amount of overprotection in the resultant risk numbers. <br />REFERENCES AND BIBLIOGRAPHY <br />Agency for Toxic Substances and Disease Registry (ATSDR), 1988. <br />Toxicological Profile for Chromium fPraft). U.S. Public Health <br />Service, January l‘^88. <br />Agency for Toxic Substances and Disease Registry (ATSDR), 1988. <br />Toxicological Profile for Lead (Draft). U.S. Public Health <br />Service, May 1988. <br />ATSDR, Toxicological Profile for Lead. Toxicological Profile for <br />Cadmium, Toxicological Profile for Arsenic (drafts), U.S. Public <br />Health Service, Agency for Toxic Substances and Disease Registry, <br />draft documents, 1988. <br />? 1