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-V -:;- .-; <br />'Mf- <br />te-'- <br />•tA. ■ <br />li-i <br />} •■ ■ <br />i-rV'. <br />v'* <br />^3'v.. <br />l7- <br />'Wf. <br />. I <br />•* ■ :> <br />j'fev <br />i'4. <br />k. <br />Y.-;r- <br />92-47.03 <br />animals, and fish within a given distance from the source <br />over a specified period of time. <br />This contaminant modeling tool is a predictive means of <br />estimating the uptake, bioconcentration, and <br />biomagnification of airborne pollutants through several <br />ecological trophic levels and exposure routes. Ultimately, <br />total human uptake (^g/day) of contaminants is estimated <br />along with the relative contributions of the various <br />exposure routes examined. Figure 2 illustrates the trophic <br />exposure pathways. <br />Three routes of vegetative uptake are considered; <br />Uptake by the plant root system <br />Wet and dry foliar deposition <br />Contaminant vapor phase uptake by the aerial portion of <br />plant <br />This model estimates uptake for animal fe d grain and forage <br />vegetation as well as crops consumed by man. It predicts <br />contaminant concentrations in animal tissue resulting from <br />inhalation and ingestion exposures. Ingestion of animal <br />tissues and crops are both included in the total human <br />exposure. <br />Calculation of aquatic deposition permits evaluation of <br />contaminant uptake by fish and, subsequently, human exposure <br />via ingest:on of contaminated fish flesh. <br />Risk Characterisation <br />The risks to human health are characterized quantitatively. <br />Quantitative risk estimates are generated through the use of <br />Carcinogenic Slope Factors and Reference Doses. <br />The ratio of Dose to Reference Dose is termed a Hazard <br />Quotient and is a measure of the potential health effects of a <br />given exposure. Thus: <br />Hazard Quotient = Dose Reference Dose <br />The hazard quotient is, therefore, simply a comparison <br />between the amount of a chemical to which a person is exposed and <br />an acceptable amoufit (RfD) published by the U.S. ERA. <br />The U.S. EPA (U.S. EPA 1989) explains that a reference dose <br />(RfD) is an "estimate (with uncertainty spanning perhaps an order <br />of magnitude or greater) of a daily exposure level for the human